1. Homocysteine and Thrombotic Disease
by Armando D'Angelo, and Jacob Selhub
Blood
Volume 90(1):1-11
July 1, 1997
©1997 by American Society of Hematology

2. Homocysteine metabolic pathways.
Homocysteine metabolic pathways. In the methylation pathway, homocysteine acquires a methyl group either from betaine, a reaction that occurs mainly in the liver or from 5-methyltetrahydrofolate, a reaction which occurs in all tissues and is vitamin B12–dependent. In the transsulfuration pathway homocysteine condenses with serine to form cystathionine in a reaction that is catalyzed by CBS and requires PLP.
Armando D'Angelo, and Jacob Selhub Blood 1997;90:1-11
©1997 by American Society of Hematology