Presentation is loading. Please wait.

Presentation is loading. Please wait.

Mechanisms of HIV-associated lymphocyte apoptosis

Similar presentations


Presentation on theme: "Mechanisms of HIV-associated lymphocyte apoptosis"— Presentation transcript:

1 Mechanisms of HIV-associated lymphocyte apoptosis
by Andrew D. Badley, André A. Pilon, Alan Landay, and David H. Lynch Blood Volume 96(9): November 1, 2000 ©2000 by American Society of Hematology

2 Schematic overview of the regulation of apoptosis.
Andrew D. Badley et al. Blood 2000;96: ©2000 by American Society of Hematology

3 T-cell apoptosis.Mechanisms of physiologic T-cell apoptosis (top) and mechanisms of increased T-cell apoptosis associated with HIV infection (bottom). T-cell apoptosis.Mechanisms of physiologic T-cell apoptosis (top) and mechanisms of increased T-cell apoptosis associated with HIV infection (bottom). VAD refers to the pan-caspase inhibitor 2-VAD-Fmk. Andrew D. Badley et al. Blood 2000;96: ©2000 by American Society of Hematology

4 Kinetics of change in CD4 T-cell number after the initiation of protease inhibitor (PI)–based HAART.
Andrew D. Badley et al. Blood 2000;96: ©2000 by American Society of Hematology


Download ppt "Mechanisms of HIV-associated lymphocyte apoptosis"

Similar presentations


Ads by Google