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Radiation Necrosis Mimicking Progressive Brain Metastasis in a Patient with Non-small Cell Lung Cancer  Kadoaki Ohashi, MD, Kastuyuki Kiura, MD, PhD,

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Presentation on theme: "Radiation Necrosis Mimicking Progressive Brain Metastasis in a Patient with Non-small Cell Lung Cancer  Kadoaki Ohashi, MD, Kastuyuki Kiura, MD, PhD,"— Presentation transcript:

1 Radiation Necrosis Mimicking Progressive Brain Metastasis in a Patient with Non-small Cell Lung Cancer  Kadoaki Ohashi, MD, Kastuyuki Kiura, MD, PhD, Nagio Takigawa, MD, PhD, Shigeki Umemura, MD, Naruhito Kondo, MD, Mistuhiro Takemoto, MD, PhD, Kensuke Onoda, MD, PhD, Motoi Aoe, MD, PhD, Masahiro Tabata, MD, PhD, Mistune Tanimoto, MD, PhD  Journal of Thoracic Oncology  Volume 2, Issue 8, Pages (August 2007) DOI: /JTO.0b013e31811f3abb Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Brain metastasis of right occipital lobe 7 months after concomitant chemoradiotherapy followed by surgery (A) had regressed once 3 months after whole-brain radiation therapy and X-knife stereotactic radiotherapy (B). However, it increased in size 9 months after whole-brain radiation therapy and X-knife stereotactic radiotherapy (C) and thereafter progressed further despite the performance of cyber-knife treatment (D). Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e31811f3abb) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 The pathological diagnosis of the brain tumor was radiation necrosis. Fibrinoid necrosis of the blood vessel walls and reactive gliosis was observed. Journal of Thoracic Oncology 2007 2, DOI: ( /JTO.0b013e31811f3abb) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions


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