1. Light micrograph of adult rat brain DAB immunostained for Reelin (blue) and counterstained with neutral red for cells (red).
Light micrograph of adult rat brain DAB immunostained for Reelin (blue) and counterstained with neutral red for cells (red). A illustrates that Reelin-positive cells are found throughout the cortical laminae but are particularly numerous in layer V. B shows a diffuse Reelin band lining the hippocampal fissure, in addition to numerous Reelin-positive cells around this fissure, in the stratum oriens, and in the hilus of the dentate gyrus. C shows a high density of Reelin-positive cells in entorhinal cortex layer II. D is a high magnification of the boxed area of B showing Reelin-positive cells and extracellular reelin around the hippocampal fissure. E is a high magnification of the box in A illustrating Reelin expressed in somata and proximal dendrites of a cortical bitufted cell. [Bars = 150 μm (A), 500 μm (B), 125 μm (C), 50 μm (D), and 25 μm (E).]
C. Pesold et al. PNAS 1998;95:6:
©1998 by National Academy of Sciences