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Validation of next-generation sequencing for comprehensive chromosome screening of embryos  Allen Kung, Santiago Munné, Brandon Bankowski, Alison Coates,

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Presentation on theme: "Validation of next-generation sequencing for comprehensive chromosome screening of embryos  Allen Kung, Santiago Munné, Brandon Bankowski, Alison Coates,"— Presentation transcript:

1 Validation of next-generation sequencing for comprehensive chromosome screening of embryos 
Allen Kung, Santiago Munné, Brandon Bankowski, Alison Coates, Dagan Wells  Reproductive BioMedicine Online  Volume 31, Issue 6, Pages (December 2015) DOI: /j.rbmo Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 Comparison of a BlueGnome array-comparative genomic hybridization (aCGH) profile to next-generation sequencing (NGS)-produced Integrated Genome Viewer (IGV) profile. An example of a blastocyst sample processed using both aCGH and NGS (Illumina microarrays and the Ion Torrent PGM). The upper panel is the graphical visualization of the NGS analysis using IGV. The lower panel is the graphical representation of the array profile. Both samples presented are scored as an XY, monosomy 4, 11, and a partial monosomy on chromosome 13 from q21.32 to q34. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions


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