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Progression of Ebola Therapeutics During the 2014–2015 Outbreak

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1 Progression of Ebola Therapeutics During the 2014–2015 Outbreak
Emelissa J. Mendoza, Xiangguo Qiu, Gary P. Kobinger  Trends in Molecular Medicine  Volume 22, Issue 2, Pages (February 2016) DOI: /j.molmed Copyright © Terms and Conditions

2 Figure 1 The Ebola Virus (EBOV) Infects Multiple Organs: A Variety of Disease Symptoms in Humans. EBOV is transmitted via direct contact with droplets of bodily fluids from infected individuals or animals. After 2–21 days of incubation, EBOV disease manifests. EBOV achieves intracellular entry into many susceptible cell types, easily enters the blood circulation, and can target multiple organs of the body, including the brain, eyes, nose, mouth, throat, heart, lungs, muscles, liver, spleen, kidney, skin, digestive tract, and joints. The diagram highlights the severity and fatality of the disease, which stems from the consequences of multiple organ failure. Trends in Molecular Medicine  , DOI: ( /j.molmed ) Copyright © Terms and Conditions


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