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The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis—a prospective multi-centre.

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Presentation on theme: "The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis—a prospective multi-centre."— Presentation transcript:

1 The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis—a prospective multi-centre European observational study  M.J. O’Dwyer, M.H. Starczewska, J. Schrenzel, K. Zacharowski, D.J. Ecker, R. Sampath, D. Brealey, M. Singer, N. Libert, M. Wilks, J.-L. Vincent  Clinical Microbiology and Infection  Volume 23, Issue 3, Pages 208.e1-208.e6 (March 2017) DOI: /j.cmi Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Twenty-eight-day mortality. Among those patients with a negative blood culture result, those with a positive PCR/ESI-MS test result have a higher mortality. A McNemar’s test was performed on the non-surviving patients, which indicated that the total number of positive tests for each method was statistically different (McNemar test statistic=45, degree of freedom=1 and p <0.0001). BC, blood culture; PCR/ESI-MS, PCR followed by electrospray ionization-mass spectrometry. Clinical Microbiology and Infection  , 208.e1-208.e6DOI: ( /j.cmi ) Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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