1. Sirolimus Pharmacokinetics in Early Postmyeloablative Pediatric Blood and Marrow Transplantation 
Rakesh K. Goyal, Kelong Han, Donna A. Wall, Michael A. Pulsipher, Nancy Bunin, Stephan A. Grupp, Sripal R. Mada, Raman Venkataramanan 
Biology of Blood and Marrow Transplantation 
Volume 19, Issue 4, Pages (April 2013)
DOI: /j.bbmt
Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

2. Figure 1
Whole-blood 0 h concentrations of sirolimus for all subjects (n = 40) over a dosing interval, individually for each patient (left) and in 4 groups (right): no fluconazole, concomitant i.v. fluconazole, concomitant oral fluconazole, and vomiting after sirolimus administration.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

3. Figure 2
Standard box-and-whisker plots showing Cl/F, Vd/F, and t1/2 of sirolimus in the ≤12-year and >12-year age groups. Solid horizontal lines represent median values.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

4. Figure 3
Standard box-and-whisker plots showing sirolimus trough concentrations and AUC0-24 in Caucasian and Hispanic patients. Solid horizontal lines represent median values.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

5. Figure 4
Standard box-and-whisker plots showing dose-normalized trough sirolimus concentrations (C0 and C24) in patients receiving concomitant fluconazole therapy and those not receiving fluconazole. Values are median and 95% CI. Solid horizontal lines represent median values.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions