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Challenges to Liver Transplantation and Strategies to Improve Outcomes

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Presentation on theme: "Challenges to Liver Transplantation and Strategies to Improve Outcomes"— Presentation transcript:

1 Challenges to Liver Transplantation and Strategies to Improve Outcomes
Philipp Dutkowski, Michael Linecker, Michelle L. DeOliveira, Beat Müllhaupt, Pierre-Alain Clavien  Gastroenterology  Volume 148, Issue 2, Pages (February 2015) DOI: /j.gastro Copyright © 2015 AGA Institute Terms and Conditions

2 Figure 1 Five-year patient - and graft survival for the most common indications for LT as reported by the European Transplant registry (ELTR).2 Data for perihilar carcinoma (PHC) is obtained from 12 US centers.58 Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2015 AGA Institute Terms and Conditions

3 Figure 2 Mayo clinic treatment scheme and outcome of patients receiving neoadjuvant treatment followed by LT for PHC. Of the 247 patients with neoadjuvant treatment, 64% could proceed to LT resulting in a five-year survival of 69%. Figure courtesy Prof. C. Rosen. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2015 AGA Institute Terms and Conditions

4 Figure 3 One year mortality after LT in relation to the balance of risk (BAR)-score.116 While post-transplant mortality remains below or equal 20% up to BAR score of 18, the risk to die after LT increases exponentially above BAR 18. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2015 AGA Institute Terms and Conditions


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