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Intravascular Survival and Extravasation of Tumor Cells

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Presentation on theme: "Intravascular Survival and Extravasation of Tumor Cells"— Presentation transcript:

1 Intravascular Survival and Extravasation of Tumor Cells
Boris Strilic, Stefan Offermanns  Cancer Cell  Volume 32, Issue 3, Pages (September 2017) DOI: /j.ccell Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Mechanisms of Intravascular Tumor Cell Survival
Three major processes affect tumor cell survival in the circulation: loss of cell anchorage (anoikis), mechanical stress, and attacks by the immune system. Shown are molecules and mechanisms for which an involvement in promoting intravascular survival of tumor cells was shown under in vivo conditions. For details, see text. Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2017 Elsevier Inc. Terms and Conditions

3 Figure 2 Mechanisms of Tumor Cell Extravasation
Shown are molecules and mechanisms for which an involvement in tumor cell extravasation was shown under in vivo conditions. For details, see text. Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2017 Elsevier Inc. Terms and Conditions


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