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Warren J. Gasper, MD, Christopher D

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1 Thirty-day vein remodeling is predictive of midterm graft patency after lower extremity bypass 
Warren J. Gasper, MD, Christopher D. Owens, MD, Ji Min Kim, MPH, Nancy Hills, PhD, Michael Belkin, MD, Mark A. Creager, MD, Michael S. Conte, MD  Journal of Vascular Surgery  Volume 57, Issue 1, Pages 9-18 (January 2013) DOI: /j.jvs Copyright © 2013 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Changes in vein graft index segment lumen diameter from 0 to 12 months. The average percentage change in lumen diameter was +24% ± 27% in the first postoperative month, dropping to ∼ 0% change after 3 months. Journal of Vascular Surgery  , 9-18DOI: ( /j.jvs ) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Vein graft index segment lumen diameter is associated with (A) race and (B) high-sensitivity C-reactive protein (hsCRP) level. Values shown represent the mean ± standard error of the mean (error bars) diameter at each assessment. A, During the 12-month study period, vein grafts of nonwhite participants had significantly smaller lumen diameters by random-effects model (−0.9 mm; 95% confidence interval [CI], −1.5 to −0.34 mm; P = .002). B, Similarly, participants with a baseline hsCRP ≥5 mg/L had significantly smaller vein graft lumen diameters by random-effects model (−0.5 mm; 95% CI, −0.98 to −0.012 mm; P = .045). Journal of Vascular Surgery  , 9-18DOI: ( /j.jvs ) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Index segment lumen diameter based on eventual loss of primary patency. Values shown represent the mean diameter ± standard error of the mean (error bars) at each interval. Although starting at a similar size as those that remained patent, vein grafts that eventually lost primary patency had a significantly smaller lumen diameter over time by random-effects model (−0.5 mm; 95% confidence interval [CI], −1.0 to −0.052 mm; P = .03). Journal of Vascular Surgery  , 9-18DOI: ( /j.jvs ) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

5 Fig 4 Early (0- to 1-month) remodeling is associated with primary patency (log-rank, P = .02). Journal of Vascular Surgery  , 9-18DOI: ( /j.jvs ) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

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