1. SURVEY OF BIOCHEMISTRY Fatty Acid Oxidation

2. Overview of Lipid Metabolism

3. Triglyceride Breakdown
Triglycerides break down into 3 fatty acids and one molecule of glycerol.

4. Activation of Fatty Acids Acyl-CoA Synthetase
Step 1

5. Activation of Fatty Acids Acyl-CoA Synthetase
Step 2

6. Carnitine as a Carrier

7. Carnitine as a Carrier

8. Fatty Acid Oxidation Saturated Fatty Acyl-CoA

9. Fatty Acid Oxidation Step 2

10. Fatty Acid Oxidation Step 3

11. Fatty Acid Oxidation Step 4

12. Examples of Unsaturated Fatty Acids

13. Oxidation of Unsaturated Fatty Acids

14. Oxidation of Unsaturated Fatty Acids

15. Oxidation of Unsaturated Fatty Acids

16. Oxidation of Unsaturated Fatty Acids
Moves the double bond!

17. Another Problem in Oxidizing Unsaturated Fatty Acids
Poor substrate for enoyl-CoA
hydratase

18. Alternative Pathway for Unsaturated Fatty Acids
Study Figure and Figure 20-15

19. Odd-Chain Fatty Acids