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A Dynamics Criterion to Determine Allostery

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Presentation on theme: "A Dynamics Criterion to Determine Allostery"— Presentation transcript:

1 A Dynamics Criterion to Determine Allostery
Ming S. Liu, Billy D. Todd, Richard S. Sadus  Biophysical Journal  Volume 96, Issue 3, Pages 426a-427a (February 2009) DOI: /j.bpj Copyright © 2009 Biophysical Society Terms and Conditions

2 Figure 1 Difference matrix of dynamic correlations in protein - the Aquifex AdK case: red, a correlated motion; blue, an anti-correlated motion; and red (blue) regions correspond to same (opposite) direction distortions. The presence of both positive and negative correlations indicates the existence of an allosteric cooperativity during conformational changes, as was proved by NMR experiments. Biophysical Journal  , 426a-427aDOI: ( /j.bpj ) Copyright © 2009 Biophysical Society Terms and Conditions

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