1. Nuclear Magnetic Resonance (NMR) Spectroscopy
• Identify the environment of hydrogen and
carbon atoms
• Identify atom connectivity
• Identify stereochemical relationships

4. An NMR Spectrometer

5. 1H NMR of Acetone

6. 1H NMR of Methyl Acetate

7. Electron Density Maps

8. Electron Shielding

10. 1H NMR of Methyl Acetate

13. 1H NMR of Ethyl Acetate 3 3 2

16. A Splitting Diagram for
a Doublet of Doublets

17. The Difference between a Quartet and a Doublet of Doublets

18. Diamagnetic Anisotropy

19. Dry, ultra-pure ethanol
Ethanol with trace acid

20. Common NMR Shifts

21. Common NMR Shifts

22. Putting It All Together

23. Putting It All Together

24. Putting It All Together

25. Four Similar Unknowns
Molecular Ion = 74 [C4H10O]

26. Unknown #1 9 1

27. Unknown #2 6 2 1 1

28. Unknown #3 3 2 1 4

29. Unknown #4 1 7 2

30. Common 13C Chemical Shifts

31. Proton Decoupling

32. 13C NMR of Ethyl Acetate

33. 13C NMR of Ethyl Acetate

34. Can we identify this compound?

35. Can we identify this compound?

36. Can we identify this compound?3 2 1 1 1

37. Can we identify this compound?86 14 62
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