1. Calcified Left Ventricular Mass: Unusual Clinical, Echocardiographic, and Computed Tomographic Findings of Primary Cardiac Osteosarcoma 
Sunil K. Nowrangi, MD, Naser M. Ammash, MD, William D. Edwards, MD, Jerome F. Breen, MD, John H. Edmonson, MD 
Mayo Clinic Proceedings 
Volume 75, Issue 7, Pages (July 2000)
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2. Figure 1
Transthoracic (left) and transesophageal (right) echocardiograms, demonstrating a large calcified left ventricular mass extending from the base of the septum to the posteromedial section of the ventricle. Left, Parasternal long-axis view. Ao = aorta; LA = left atrium; LV = left ventricle; RA = right atrium; RV = right ventricle.
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3. Figure 2
Noncontrast (left) and contrast-enhanced (right) computed tomograms of heart, showing partially calcified mass (arrows). The small amount of associated noncalcified soft tissue was originally thought to be part of the papillary muscle process.
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4. Figure 3
Follow-up contrast-enhanced computed tomogram of chest, showing that the partially calcified mass (left) (arrows) has increased in size and that a new nodule (right) (arrowheads) has developed.
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5. Figure 4
Gross photograph of ventricular slices (short-axis format). Osteosarcoma (white) is massive and involves the inferoseptal aspects of both ventricles, at midventricular and apical levels, and the posteromedial mitral papillary muscle.
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6. Figure 5
Photomicrograph of primary cardiac osteosarcoma. Malignant spindle cells are associated with focal bone formation (hematoxylin-eosin; original magnification ×300).
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