1. Nerve conduction block in diabetic rats using high-intensity focused ultrasound for analgesic applications 
Y-F. Lee, C-C. Lin, J-S. Cheng, G-S. Chen 
British Journal of Anaesthesia 
Volume 114, Issue 5, Pages (May 2015)
DOI: /bja/aeu443
Copyright © 2015 The Author(s) Terms and Conditions

2. Fig 1
The experimental configuration used for in vitro nerve treatment with high-intensity focused ultrasound (HIFU). The sciatic notch was placed in the central chamber of the nerve platform and sonicated using top-down HIFU. A needle thermocouple was used to monitor the temperature of the Ringer solution in the central chamber. CAPs, compound action potentials; SAPs, sensory action potentials.
British Journal of Anaesthesia  , DOI: ( /bja/aeu443)
Copyright © 2015 The Author(s) Terms and Conditions

3. Fig 2
The temporal courses of the CAP and SAP peaks after HIFU exposure of nerves from control (a) and diabetic rats (b) in vitro. The incident HIFU parameters for the control and diabetic nerves were 2290 W cm−2 for 4 s and 1850 W cm−2 for 4 s, respectively. Median values and ranges are shown (n=12).
British Journal of Anaesthesia  , DOI: ( /bja/aeu443)
Copyright © 2015 The Author(s) Terms and Conditions

4. Fig 3
The temporal courses for days 1 (a), 7 (b), 14 (b), and 28 (b) of the compound muscle action potential (CMAP) peaks of control rat nerves in vivo after an HIFU exposure of 2290 W cm−2 for 7 s (diamonds), 12 s (squares), and 18 s (triangles). n=6 for each HIFU parameter. *Significantly different from day 1.
British Journal of Anaesthesia  , DOI: ( /bja/aeu443)
Copyright © 2015 The Author(s) Terms and Conditions

5. Fig 4
The temporal courses for days 1 (a), 7 (b), 14 (b), and 28 (b) of the CMAP peaks of diabetic rat nerves in vivo after an HIFU exposure of 2810 W cm−2 for 3 (diamonds), 5 (squares), and 8 s (triangles). n=6 for each HIFU parameter. *Significantly different from day 1.
British Journal of Anaesthesia  , DOI: ( /bja/aeu443)
Copyright © 2015 The Author(s) Terms and Conditions

6. Fig 5
Photomicrographs of haematoxylin- and eosin-stained sections of a representative control rat sciatic nerve on day 1 after HIFU (2290 W cm−2 for 7 s; a) and on day 28 after HIFU (2290 W cm−2 for 18 s; b). (c) A diabetic rat nerve on day 1 after HIFU (2810 W cm−2 for 3 s). (d), (e), and (f) Enlarged images (×400) of a local region of (a), (b), and (c).
British Journal of Anaesthesia  , DOI: ( /bja/aeu443)
Copyright © 2015 The Author(s) Terms and Conditions