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Published byKevin Bernd Bergmann Modified over 6 years ago
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Reporting Live from the Epidermal Stem Cell Compartment!
Robert P. Fordham, Kim B. Jensen Cell Stem Cell Volume 11, Issue 2, Pages (August 2012) DOI: /j.stem Copyright © 2012 Elsevier Inc. Terms and Conditions
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Figure 1 Live Imaging as a Tool to Interrogate Stem Cell Behavior in the Epidermis The study by Rompolas et al. uses two-photon microscopy to track cell behavior in the hair follicle stem cell niche (1 and 2) and in stem cell progeny (3 and 4) and to investigate the functionality of the epithelial-mesenchymal interactions in regeneration (5). The technique of two-photon microscopy described here can now be utilized to address unresolved questions in skin stem cell biology, particularly the relationship between different stem cell compartments (6, 7, and 8). Moreover, laser-mediated cell ablation provides a tool to probe the relevance of the immediate microenvironment on stem cell behavior (9 and 10). Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2012 Elsevier Inc. Terms and Conditions
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