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Advances in Dyslipidemia: What Have We Learned From ACC 2017

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Presentation on theme: "Advances in Dyslipidemia: What Have We Learned From ACC 2017"— Presentation transcript:

1 Advances in Dyslipidemia: What Have We Learned From ACC 2017

2 PCSK9 Inhibitors – Leading Up to Recent Outcomes Data

3 Intensive vs Standard Statin Therapy

4 GLAGOV Effect of PCSK9 Inhibitors on CHD Progression

5 IVUS Trials How Low Is Too Low When Lowering LDL-C?

6 Guidelines to Manage Dyslipidemia

7 SPIRE: Bococizumab CV Outcomes

8 FOURIER: Cardiovascular Outcomes With PCSK9 Inhibition

9 FOURIER Trial Design

10 FOURIER: LDL-C Reduction

11 FOURIER: CV Outcomes

12 FOURIER: Lower LDL-C Is Better

13 Clinical Implications of FOURIER

14 Safety of PCSK9 Monoclonal Antibodies

15 FOURIER: Safety

16 EBBINGHAUS Cognitive Study of Patients Enrolled in FOURIER Trial: Endpoints

17 Primary Endpoint Spatial Working Memory Strategy Index

18 Cognitive Assessments by Achieved LDL-C and Treatment

19 IMPROVE-IT Long-Term Efficacy and Safety

20 Abbreviations

21 Abbreviations (cont)


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