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Certolizumab Pegol in Patients With Moderate to Severe Crohn's Disease and Secondary Failure to Infliximab  William J. Sandborn, Maria T. Abreu, Geert.

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Presentation on theme: "Certolizumab Pegol in Patients With Moderate to Severe Crohn's Disease and Secondary Failure to Infliximab  William J. Sandborn, Maria T. Abreu, Geert."— Presentation transcript:

1 Certolizumab Pegol in Patients With Moderate to Severe Crohn's Disease and Secondary Failure to Infliximab  William J. Sandborn, Maria T. Abreu, Geert D'Haens, Jean–Frédéric Colombel, Severine Vermeire, Krassimir Mitchev, Corinne Jamoul, Richard N. Fedorak, Martina E. Spehlmann, Douglas C. Wolf, Scott Lee, Paul Rutgeerts  Clinical Gastroenterology and Hepatology  Volume 8, Issue 8, Pages e2 (August 2010) DOI: /j.cgh Copyright © 2010 AGA Institute Terms and Conditions

2 Supplementary Figure 1 Study flow diagram. ae, adverse event; loe, lack/loss of efficacy; ltfu, lost to follow-up evaluation; q2w, every 2 weeks; q4w, every 4 weeks; woc, withdrawal of consent. Clinical Gastroenterology and Hepatology 2010 8, e2DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

3 Figure 1 Response and remission rates (A) over the open-label induction phase (n = 539) and (B) at week 26 (n = 329). Clinical Gastroenterology and Hepatology 2010 8, e2DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions

4 Figure 2 CDAI scores over time (n = 329).
Clinical Gastroenterology and Hepatology 2010 8, e2DOI: ( /j.cgh ) Copyright © 2010 AGA Institute Terms and Conditions


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