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Reduced endothelial progenitor cells in extracranial arterial stenosis but not intracranial arterial stenosis  Zhixin Huang, MD, PhD, Xiaohao Zhang, MD,

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Presentation on theme: "Reduced endothelial progenitor cells in extracranial arterial stenosis but not intracranial arterial stenosis  Zhixin Huang, MD, PhD, Xiaohao Zhang, MD,"— Presentation transcript:

1 Reduced endothelial progenitor cells in extracranial arterial stenosis but not intracranial arterial stenosis  Zhixin Huang, MD, PhD, Xiaohao Zhang, MD, Haixia Zhang, MD, Ruidong Ye, MD, PhD, Yunyun Xiong, MD, PhD, Wen Sun, MD, PhD, Yongkun Li, MD, PhD, Xinfeng Liu, MD, PhD  Journal of Vascular Surgery  Volume 62, Issue 6, Pages (December 2015) DOI: /j.jvs Copyright © 2015 Society for Vascular Surgery Terms and Conditions

2 Fig 1 CD45−/dimCD34+CD309+ cells (left panel), CD45−/dimCD133+CD309+ cells (middle panel), and CD45−/dimCD34+CD133+CD309+ cells (right panel) detected in peripheral blood by flow cytometry. The acquisition goal was 1 × 106 events. Blood cells were stained with fluorescein-labeled monoclonal antibodies and processed as described in the text. Gates were drawn on the lymphocyte population based on CD45 and side-scatter or CD34. Within these gates, CD34+ and CD133+ elements expressing CD309 were analyzed. Percentage positive cells were defined by setting lower limits on the basis of negative isotype controls. CD34+CD309+, CD133+CD309+, and CD34+CD133+CD309+ cells are located in the upper right quadrants (Q2 represents the frequency of parent gated population, but not total events). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Box plot shows lower median endothelial progenitor cells (EPCs) levels in patients with cerebral atherosclerosis (CA). Bottom of box = 25th percentile; top of box = 75th percentile; horizontal line = median. EAS, Extracranial arterial stenosis; IAS, intracranial arterial stenosis. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

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