1. Food Allergy: Facts and Fiction*
RICHARD A. SCHREIBER, M.D., F.R.C.P.(C), W. ALLAN WALKER, M.D. 
Mayo Clinic Proceedings 
Volume 64, Issue 11, Pages (November 1989)
DOI: /S (12)
Copyright © 1989 Mayo Foundation for Medical Education and Research Terms and Conditions

2. Fig. 1
IgA plasma cell cycle. Lymphocytes (L) within Peyer's patches (PP) are stimulated by intestinal antigens entering by means of specialized epithelial (M) cells (1). Lymphoblasts migrate to mesenteric nodes for further maturation (2), enter the systemic circulation, and then migrate back to the lamina propria (3), where they produce secretory IgA in response to intestinally absorbed antigens.
(Modified from Walker and Isselbacher.27 By permission of the New England Journal of Medicine.)
Mayo Clinic Proceedings  , DOI: ( /S (12) )
Copyright © 1989 Mayo Foundation for Medical Education and Research Terms and Conditions

3. Fig. 2
Pathologic antigen interaction with intestinal surface. Disrupted intestinal mucosal barrier can predispose to excessive uptake of dietary antigens into the systemic circulation. T-cell modulation of the B-cell response can enhance the systemic IgE/IgG response and result in immunoresponsiveness rather than tolerance to dietary antigens.
(Modified from Walker.19 By permission of the American College of Allergy and Immunology.)
Mayo Clinic Proceedings  , DOI: ( /S (12) )
Copyright © 1989 Mayo Foundation for Medical Education and Research Terms and Conditions