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From the 2015 Conferences to the Clinic

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Presentation on theme: "From the 2015 Conferences to the Clinic"— Presentation transcript:

1 From the 2015 Conferences to the Clinic

2 Program Goals

3 A Double-Blind, Randomized, Placebo-Controlled, Flexible-Dose Study of Vilazodone in Patients With GAD

4 Vilazodone-GAD Randomized Controlled Trial Results Efficacy

5 Vilazodone-GAD Randomized Controlled Trial Improvement in Functional Domains

6 From the 2015 Conferences to the Clinic

7 Post hoc Analyses of Suicidality in Clinical Trials of Vilazodone

8 Suicidality in Vilazodone Clinical Trials

9 Levomilnacipran ER Treatment in Adult Patients With First-Episode, Highly Recurrent, and Chronic MDD

10 Levomilnacipran ER

11 Efficacy of Vortioxetine in the Treatment of Patients With MDD in Short-term Placebo-Controlled Studies: A Meta-analysis of 11 Studies

12 Efficacy of Vortioxetine Results

13 From the 2015 Conferences to the Clinic

14 Lurasidone for the Treatment of MDD With Mixed Features A Randomized, Double-Blind, Placebo-Controlled, 6-Wk Trial

15 Lurasidone for the Treatment of MDD With Mixed Features A Randomized, Double-Blind, Placebo-Controlled, 6-Wk Trial (cont)

16 Patterns of Antidepressant Efficacy With Quetiapine ER as Adjunct to Different Ongoing Antidepressants: Exploration of MOA Hypotheses

17 Patterns of Antidepressant Efficacy With Quetiapine ER as Adjunct to Different Ongoing Antidepressants: Exploration of MOA Hypotheses (cont)

18 Efficacy and Safety of Cariprazine as Adjunctive Therapy in MDD A Double-Blind, Randomized, Placebo-Controlled Study

19 From the 2015 Conferences to the Clinic

20 Metabolic Tolerability Profile of Adjunct Brexpiprazole (OPC-34712) in MDD Study Design

21 Metabolic Tolerability Profile Results

22 Metabolic Tolerability Profile Results (cont)

23 Efficacy and Safety of Brexpiprazole (OPC-34712) as Adjunctive Treatment in MDD Pooled Analysis of 2 Pivotal Studies

24 Efficacy and Safety of Brexpiprazole Results

25 Abbreviations

26 Abbreviations (cont)

27 References

28 References (cont)

29 References (cont)


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