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Global Projections for Diabetes:

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Presentation on theme: "Global Projections for Diabetes:"— Presentation transcript:

1 Global Projections for Diabetes: 2003-2025

2 Efficacy of DPP-4 Inhibitor Therapy Added to Metformin

3 DPP-4 Inhibitors vs SUs Added to Metformin: 2-Year Results

4 Glycemic Control With GLP-1 RAs: Head-to-Head Studies

5 Efficacy and Safety: SGLT2 Inhibitor vs Sitagliptin (DPP-4 Inhibitor) Added to Metformin

6 SGLT2 Inhibitor vs SU Added to Metformin

7 Effect of Liraglutide Dose on Mean Weight Change Response

8 SGLT2 Inhibitor Pooled Data: Weight Reduction in Placebo-Controlled Studies

9 SGLT2 Inhibitor: Weight Loss Is Mostly Fat

10 DPP-4 Inhibitor vs SGLT2 Inhibitor: Effect on SBP in T2DM

11 SAVOR-TIMI 53: Primary Endpoint

12 SAVOR-TIMI 53: Hospitalization for HF

13 EXAMINE: Primary Endpoint

14 EXAMINE: Hospitalization for HF

15 TECOS: Effect of Sitagliptin vs Placebo on CV Outcomes in T2DM

16 TECOS: Hospitalization for HF

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19 EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on the Primary Composite Outcome

20 EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on CV Death

21 EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on All-Cause Mortality

22 EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on HF Hospitalization

23 DUAL-I: HbA1c Comparison

24 DUAL-I: Percentage of Patients to Target HbA1c

25 DUAL-I: Change in Body Weight

26 DUAL-I: Confirmed Hypoglycemia

27 DUAL-I: Nausea Over 26 Weeks


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