1. SAVE: Risk of total mortality associated with reduced kidney function
GFR (mL/min/1.73m2)
Multivariate adjusted risk ratio
95% CI
>75
Ref
60-74
1.11
45-59
1.24
<45
1.81
p for trend
0.001
Tokmakova MP et al. Circulation 2004; available at

2. SAVE: Events prevented by captopril treatment in subjects with and without chronic kidney disease
End point
With CKD
Without CKD
CV events prevented per 100 subjects treated with captopril
12.4
5.5
Tokmakova MP et al. Circulation 2004; available at