1. Rash and Fever: Clues to an Elusive Hematologic Malignancy
Samantha C. Shapiro, MD, Ibironke Oduyebo, MD, Rima Koka, MD, PhD, Allan C. Gelber, MD 
The American Journal of Medicine 
Volume 129, Issue 4, Pages e5-e8 (April 2016)
DOI: /j.amjmed
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1
Anterior view of bilateral legs showing an erythematous, morbilliform, pruritic rash that also encompassed the arms, trunk, and back.
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3. Figure 2
Whole-body positron emission tomography scan, coronal view. Diffuse fluorodeoxyglucose uptake in the spleen, inguinal, axillary, cervical, and hilar lymph nodes, and pulmonary lymphatics.
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4. Figure 3
The lymph node demonstrates atretic germinal centers with penetrating vessels. The germinal centers are surrounded by mantle zone lymphocytes and resemble the histologic feature of “onion skinning” (hematoxylin–eosin), features characteristic of the hyaline vascular variant of Castleman's disease.
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5. Figure 4
Immunohistochemistry of the lymph node tissue demonstrates CD3-positive T cells (A), aberrantly dim CD5 expression (B), and near-complete loss of CD7 expression (C).
The American Journal of Medicine  , e5-e8DOI: ( /j.amjmed )
Copyright © 2016 Elsevier Inc. Terms and Conditions