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Paul M. George, Gary K. Steinberg  Neuron 

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Presentation on theme: "Paul M. George, Gary K. Steinberg  Neuron "— Presentation transcript:

1 Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments 
Paul M. George, Gary K. Steinberg  Neuron  Volume 87, Issue 2, Pages (July 2015) DOI: /j.neuron Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Pathophysiology of Stroke
Neuron  , DOI: ( /j.neuron ) Copyright © 2015 Elsevier Inc. Terms and Conditions

3 Figure 2 Temporal Profile of Changes Induced by Neural Stem Cell Enhanced Stroke Recovery This figure was courtesy of Horie et al., Neurological behavior indicates motor recovery. The asterisk indicates that Avastin affected all parameters except for the ones marked; two asterisks indicate the inconclusive effects of Avastin. BBB, blood-brain barrier; βDG, β-dystroglycan; BVD, blood vessel density; Iba-1, ionized calcium binding adaptor molecule 1; Tie-2, a receptor tyrosine kinase; VEGF, vascular endothelial growth factor. Neuron  , DOI: ( /j.neuron ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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