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Human Naive Embryonic Stem Cells: How Full Is the Glass?

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Presentation on theme: "Human Naive Embryonic Stem Cells: How Full Is the Glass?"— Presentation transcript:

1 Human Naive Embryonic Stem Cells: How Full Is the Glass?
Yixuan Wang, Shaorong Gao  Cell Stem Cell  Volume 18, Issue 3, Pages (March 2016) DOI: /j.stem Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Derivation of Human Pluripotent Cells with Naive Properties
Human naive pluripotent cells can be derived from individual ICM cells of pre-implantation embryos in the t2iLGöY condition, or from ICM or primed PSCs in the 5iLAF condition. The naive cells reverted from primed hESCs or derived from ICMs in 5iLAF, characterized by loss of SSEA4 expression, exhibit a methylation landscape with little similarities to that of the blastocyst as well as loss of imprinting. Cell Stem Cell  , DOI: ( /j.stem ) Copyright © 2016 Elsevier Inc. Terms and Conditions


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