1. Summary of Cell Cycle and its Regulation
AP Biology

2. Review of Cell Cycle

3. Sample Question
If the S phase were eliminated from the cell cycle, the daughter cells would
Have half the genetic material found in the parent cell
Be genetically identical to each other
Be genetically identical to the parent
Synthesize the missing genetic material on their own

4. Sample Question
Select from one of the choices that best fits the description
Telophase
Interphase
Cytokinesis
Prophase
Anaphase
Descriptions
Cytokinesis during this final stage of mitosis
Division of cytoplasm
Sister chromatids separate
Genetic material replicates

5. Checkpoints

6. Sample Questions
After which of the following checkpoints in the cell cycle is the cell first committed to divide?
G2 checkpoint
M checkpoint
Interphase checkpoint
G1 checkpoint
MPF checkpoint

7. Maturation Promoting Factor (MPF)
Composed of cyclin bound to a cyclin dependent protein kinase
CDK
constant concentration
Active only when bound to cyclin
Cyclin
Concentration varies during the cell cycle

8. Changes in Cyclin Concentration

9. Practice Problem
Look at Figure 7.9 in your handout and read through the investigation
What was the purpose of radioactive labeling
Why would you expect more radioactive labeling of DNA during S phase
What were the percentages of cells in S phase in each of three experiments provided?
What does that suggest in terms of control of cell cycle?

10. Questions?????