1. Genetic Disorder Research
Chapter 7 and 8
Date
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Notes 7.1/ Vocab. * 1
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WS Vocab Practice ** 2
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100 Greatest Discoveries Genetics 10 3
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Huntington Disease 4
Study Guide 7.1 5
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Power Notes 6
Study Guide 7.2 7
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WS Rabbit Coat Color 8
Quiz Ch 7.1 and 7.2 9
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Genetic Disorder Research
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Power Notes 8.2 11
Study Guide 8.2 12
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Power Notes 8.3 Replication 13
Study Guide 8.3 14
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Power Notes 8.4 Transcription 15

2. Section 8-4 “Transcription”

3. KEY CONCEPT Transcription converts a gene into a single-stranded RNA molecule

4. KEY CONCEPT Transcription converts a gene into a single-stranded RNA molecule

5. Direction of Translation
RNA Polymerase
RNA Nucleotides
Direction of Translation

6. RNA carries DNA’s instructions
The central dogma is the basic concept proposed by Francis Crick (one of the scientists that discovered DNA)
It states that: information flows in one direction from DNA to RNA to proteins

7. Molecular Biology
Central Dogma

8. RNA is a link between DNA and proteins
The central dogma (idea) includes three processes:
Replication
Transcription
Translation
replication
transcription
translation
RNA is a link between DNA and proteins

9. RNA differs from DNA in 3 ways:
RNA has a ribose sugar
RNA has uracil (U) instead of thymine (T)
RNA is a single-stranded structure

10. has uracil (U) instead of thymine is a single-stranded structure
Power Notes
(interprets)
(converts)
2. RNA
translation
5. Protein
transcription
(copies)
has a ribose sugar
has uracil (U) instead of thymine
is a single-stranded structure
has a deoxyribose sugar
has A, C, G, T
is a double-stranded structure

11. Transcription makes three types of RNA
Transcription copies DNA to make a strand of RNA

12. Transcription is catalyzed (is started) by RNA polymerase
RNA polymerase and other proteins form a transcription complex
The transcription complex recognizes the start of a gene and unwinds a segment of it
start site
nucleotides
transcription complex

13. RNA polymerase moves along the DNA
Nucleotides pair with one strand of the DNA
RNA polymerase bonds the nucleotides together
The DNA helix winds again as the gene is transcribed
DNA
RNA polymerase moves along the DNA

14. The RNA strand detaches from the DNA once the gene is transcribed

15. 7. RNA polymerase 5. Nucleotide 4. DNA molecule
6. Newly synthesized RNA strand
5. Nucleotide
4. DNA molecule

16. 1. RNA polymerase and other proteins recognizes the start of a gene and begins to unwind the segment of DNA.
2. RNA polymerase reads one side of the DNA template and strings complementary strand of RNA nucleotides. The growing RNA strand hangs freely as it is transcribed. Then the DNA strand closes back together.
3. The RNA strand detaches from the DNA once the gene is transcribed

17. Possible Videos to show on youtube

18. The transcription process is similar to replication
Transcription and replication both involve complex enzymes and complementary base pairing
The two processes have different end results
Replication copies all the DNA
Transcription copies one gene
Replication makes one copy
Transcription can make many copies

20. Transcription makes 3 types of RNA:
1. Messenger RNA (mRNA) carries the message that will be translated to form a protein
2. Ribosomal RNA (rRNA) forms part of ribosomes where proteins are made
3. Transfer RNA (tRNA) brings amino acids from the cytoplasm to a ribosome

21. http://learn.genetics.utah.edu/content/begin/dna/transcribe/ one gene
growing RNA strands
DNA
one
gene