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Of Brains and Blood: Developmental Origins of Glioma Diversity?

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1 Of Brains and Blood: Developmental Origins of Glioma Diversity?
Mariella G. Filbin, Charles D. Stiles  Cancer Cell  Volume 28, Issue 4, Pages (October 2015) DOI: /j.ccell Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Glioblastoma Diversity Arising from Differentially Restricted Progenitor Cells Schematic of sagittal mouse brain slice showing that two different glioblastoma subtypes (type 1 gliomas and type 2 gliomas) can be generated by stem cells or differentially restricted progenitor cells with identical driver mutations. NSC, neural stem cell; NPC, neural progenitor cell; OPC, oligodendrocyte progenitor cell; SVZ, subventricular zone; SGZ, subgranular zone. Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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