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Drosophila Development: Embryogenesis

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Presentation on theme: "Drosophila Development: Embryogenesis"— Presentation transcript:

1 Drosophila Development: Embryogenesis

2 Segmental larva organization

3 Relationship between larval segments and adult structures

4 Body plan is determined by Maternal-effect and Zygotic-effect Genes

5 Follicle cells determine assymetric structure of the egg
Egg Structure Oogenesis

6 Posterior Cytoplasmic Structures Determine Germ Cell Fate

7 A Gradient of Nuclear dorsal transcription factors determines the Dorsal Ventral Axis

8 Ventrally-located Follicle Cells Determine Nuclear dorsal through toll signalling pathway

9 Bicoid and Hunchback Gradients Determine Anterior Cell Fates
Nanos (NOS) Gradient Determines HB-M gradient

10 3’ UTR determines localization of bicoid and nanos mRNA

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12 Sequential Induction by Regulatory Proteins Determines and Refines the body plan

13 GAP gene mRNA localization

14 Pair-rule Protein Localization

15 Loss of function mutant phenotypes

16 Wild Type Fly

17 Homeotic Mutant

18 Homeobox Gene Clusters Also Regulate Body Plan in Vertebrates

19 Anterior to Posterior Expression of HOX genes in developing mouse


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