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Michael F. Nentwich, MD, Benjamin A. Bohn, MD, Faik G

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1 Lymphatic invasion predicts survival in patients with early node-negative non–small cell lung cancer 
Michael F. Nentwich, MD, Benjamin A. Bohn, MD, Faik G. Uzunoglu, MD, Matthias Reeh, MD, Alexander Quaas, MD, Tobias J. Grob, MD, PhD, Daniel Perez, MD, Asad Kutup, MD, Maximilian Bockhorn, MD, Jakob R. Izbicki, MD, FACS, FRCS, Yogesh K. Vashist, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 146, Issue 4, Pages (October 2013) DOI: /j.jtcvs Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Flow diagram demonstrating the exclusion of patients. L, Lymphatic; V, vascular; NSCLC, non–small cell lung cancer; BAC, bronchioloalveolar carcinoma. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Representative tissue sections of non–small cell lung cancer tumors with the presence of lymphatic invasion stained by the hematoxylin-eosin methods (A and B) and with the monoclonal antibody D2-40 (C and D). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Estimated overall survival according to lymphatic invasion (P = .000) (A), vascular invasion (P = .008) (B), lymphatic invasion for Union for International Cancer Control (UICC) stage IA tumors (P < .000) (C), and lymphatic invasion for UICC stage IB tumors (P = .028) (D) (log-rank test, including 95% confidence intervals). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

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