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By: Rosie, Laura, Kelly and cassandra

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1 By: Rosie, Laura, Kelly and cassandra
The cytoskeleton By: Rosie, Laura, Kelly and cassandra

2 Our structure Cytoskeleton is made up of three main structures:
Microtubules: these are hollow tubes with walls that are composed of 13 tubulin columns. Microfilaments: these are made of 2 strands of actin that are intertwined. Intermediate filaments: these are thick cables made of supercoiled fibrous proteins from the keratin family.

3 Our function Our main function is to support and maintain the cell's shape. This is extremely important to the concept of structure fits function. The microtubules are compression-resisting, while the microfilaments and intermediate filaments are tension-bearing. These are the conflicting forces that help balance the cytoskeleton.

4 The functions of microtubules
Specialized arrangements of microtubules create the cilia and flagella that are responsible for cell motility. Microtubules Help prepare the cell for division through movement and separation of chromosomes. They provide tracks for organelles with motor proteins to travel along. For example, microtubules help guide secretory vesicles from the Golgi to the plasma membrane.

5 The functions of microfilaments
Microfilaments create the core of microvilli which increases the surface area of certain cells that transport materials across the plasma membrane (ex. Intestinal cells). Responsible for changes in cell shape. Muscle contraction occur when actin filaments move toward each other. Cell motility through pseudopod is It aids in cytoplasmic streaming. Microfilaments are stained green. Mitochondria is red and DNA is blue.

6 The functions of intermediate filaments
Intermediate filaments are permanent fixtures that help support the cell's shape. They are the key components for maintaining a cell's specific shape for performing a specific function. They Anchor the nucleus and additional organelles into place. It Also forms the nuclear lamina. The vimentin (intermediate filaments) are stained red, and actin is green.

7 Our contribution to the cell
Without the cytoskeleton, the cell would lose its support and structure. If the cell lost its structure, then it could lose its function entirely. In addition, the cell’s organelles would not be set into their proper location and this could disrupt its productivity. Since the cytoskeleton is also responsible for guiding transport proteins to their proper locations, the proteins would not be able to reach their destinations and efficiently carry out their functions without it. For example, the hydrolytic enzymes found in lysosomes would never reach their specified location without the tracks provided by the cytoskeleton. It also creates vesicles from the plasma membrane that is used for phagocytosis. Cells would also not be able to properly carry out cell division.

8 Ribosomes…messing up since early life
Ribosomes are the protein factories in the cell. ribosomes are also very unreliable, as they can mutate and become damaged. These mutated ribosomes can cause serious illnesses which are sometimes fatal. There Is an increase in the number of diseases associated with ribosomes yearly. Ribosomes have been linked to early onset of Alzheimer's, diamond-Blackfan anemia, and even gastric cancer, along with many other diseases.

9 -Robert S. Fischer and Velia M. Fowler
biophysical and biochemical properties of the cytoskeleton are inseparable and play profound roles in cellular physiology. -Robert S. Fischer and Velia M. Fowler

10 "We support you, so why don't you support us?"
Vote cytoskeleton 2016


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