1. Consultant, Uveitis Service
Toxoplasmosis
Dr. Rathinam Sivakumar
HOD - Uveitis Services
Dr. Radhika. T
Consultant, Uveitis Service
Dr. Vedhanayaki Rajesh

2. Ocular History
37 year old female
OD:
defective vision – 15 days duration
pain and redness – 6 days duration

3. First Presentation IOP: OD 10mm Hg; OS 12mm Hg OD:
VA: OD 3/60 OS 6/6
IOP: OD 10mm Hg; OS 12mm Hg
OD:
pigmented KP's, AVF 2+ cells
fundus: retinochoroiditis over the macula
OS: quiet

4. Investigations
Routine baseline investigations
TC,DC,ESR,Mantoux and TPHA: within normal limits

6. Diagnosis
Toxoplasma retinochoroiditis

7. Therapy
Azithromycin 500mg OD for 15 days
Bactrim DS BD for 6 weeks
Oral Prednisolone tapered weekly from 40mg/week to 10mg (4 weeks)

8. Final Presentation – After 6 Weeks
VA: OD 6/60, OS: 6/6
IOP: OD 10mm Hg; OS 12mm Hg
OD: AC – quiet;
no vitreous cells
scar over the macula
OS: quiet

10. Conclusion Most cases of toxoplasmosis are acquired after birth
Contaminated water is the source of infection
Immunocompetent patients present with focal
retinitis, while immunosuppressed patients present
with multifocal bilateral lesions
Diagnosis is mainly CLINICAL
PCR from vitreous aspirate for atypical situations
Anti-toxoplasmic therapy with systemic steroid is the currently available treatment