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Association Between Serum Cortisol and Testosterone Levels, Opioid Therapy, and Symptom Distress in Patients with Advanced Cancer  Rony Dev, DO, David.

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Presentation on theme: "Association Between Serum Cortisol and Testosterone Levels, Opioid Therapy, and Symptom Distress in Patients with Advanced Cancer  Rony Dev, DO, David."— Presentation transcript:

1 Association Between Serum Cortisol and Testosterone Levels, Opioid Therapy, and Symptom Distress in Patients with Advanced Cancer  Rony Dev, DO, David Hui, MD, Shalini Dalal, MD, Zohra I. Nooruddin, MD, Sriram Yennurajalingam, MD, Egidio Del Fabbro, MD, Eduardo Bruera, MD  Journal of Pain and Symptom Management  Volume 41, Issue 4, Pages (April 2011) DOI: /j.jpainsymman Copyright © 2011 U.S. Cancer Pain Relief Committee Terms and Conditions

2 Fig. 1 Conceptual model for the effects of opioids on the HPA and gonadal axes in patients with advanced cancer. M=mu-opioid receptor, κ=kappa-opioid receptor, GnRH=gonadotropin-releasing hormone, ACTH= adrenocorticotropic hormone, FSH=follicle-stimulating hormone, LH=luteinizing hormone. Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman ) Copyright © 2011 U.S. Cancer Pain Relief Committee Terms and Conditions

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