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Acceleration of Umbilical Cord Blood (UCB) Stem Engraftment: Results of a Phase I Clinical Trial with Stemregenin-1 (SR1) Expansion Culture  John E. Wagner,

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Presentation on theme: "Acceleration of Umbilical Cord Blood (UCB) Stem Engraftment: Results of a Phase I Clinical Trial with Stemregenin-1 (SR1) Expansion Culture  John E. Wagner,"— Presentation transcript:

1 Acceleration of Umbilical Cord Blood (UCB) Stem Engraftment: Results of a Phase I Clinical Trial with Stemregenin-1 (SR1) Expansion Culture  John E. Wagner, MD, Claudio Brunstein, MD, PhD, David McKenna, MD, Darin Sumstad, Suzanne Maahs, PharmD, Mary J. Laughlin, MD, Michael S. Perry, DVM, PhD, FRCVS, Anthony E. Boitano, PhD, Michael Cooke, PhD, Conrad C. Bleul, MD  Biology of Blood and Marrow Transplantation  Volume 21, Issue 2, Pages S48-S49 (February 2015) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure Hematopoietic Recovery Panels A and B: Rate of neutrophil and platelet recovery compared to double UCB transplant historical controls. Panels C and D: Comparison of CD34 cell dose and days to neutrophil recovery segregated by SR-1 versus unmanipulated (UMN) unit predominance. Symbols indicate patients transplanted with SR1 plus a companion UMN UCB unit (•) and those with SR-1 UCB as a ‘stand alone’ graft (▲). Biology of Blood and Marrow Transplantation  , S48-S49DOI: ( /j.bbmt ) Copyright © Terms and Conditions

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