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“Toll”-erance in the Skin

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1 “Toll”-erance in the Skin
Tina L. Sumpter, Louis D. Falo  Immunity  Volume 41, Issue 5, Pages (November 2014) DOI: /j.immuni Copyright © 2014 Elsevier Inc. Terms and Conditions

2 Figure 1 S. aureus Recruits MDSCs to the Skin
Interactions between S. aureus and TLR2/6 heterodimers on keratinocytes cause release of IL-6, CCL22, and CCL28. These factors expand and recruit MDSCs to the skin. MDSCs in turn suppress T cell expansion via a NO-dependent mechanism. Immunity  , DOI: ( /j.immuni ) Copyright © 2014 Elsevier Inc. Terms and Conditions

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