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Circ Cardiovasc Interv

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Presentation on theme: "Circ Cardiovasc Interv"— Presentation transcript:

1 Circ Cardiovasc Interv
A New Tool for the Risk Stratification of Patients With Complex Coronary Artery DiseaseClinical Perspective by Scot Garg, Giovanna Sarno, Hector M. Garcia-Garcia, Chrysafios Girasis, Joanna Wykrzykowska, Keith D. Dawkins, Patrick W. Serruys, and Circ Cardiovasc Interv Volume 3(4): August 17, 2010 Copyright © American Heart Association, Inc. All rights reserved.

2 Kaplan Meier curves for death (A), repeat revascularization (B), myocardial infarction (MI) (C), and major adverse cardiovascular and cerebrovascular events (MACCE) (D) at 1800-day follow-up stratified accord to CSS tertile. Kaplan Meier curves for death (A), repeat revascularization (B), myocardial infarction (MI) (C), and major adverse cardiovascular and cerebrovascular events (MACCE) (D) at 1800-day follow-up stratified accord to CSS tertile. Scot Garg et al. Circ Cardiovasc Interv. 2010;3: Copyright © American Heart Association, Inc. All rights reserved.

3 ROC curve for the SYNTAX score, ACEFSCr, and CSS for mortality (A) and MACCE (B).
ROC curve for the SYNTAX score, ACEFSCr, and CSS for mortality (A) and MACCE (B). The use of the CSS leads to an improvement in the C-statistic for both outcomes. Scot Garg et al. Circ Cardiovasc Interv. 2010;3: Copyright © American Heart Association, Inc. All rights reserved.

4 Kaplan-Meier curve showing the 5-year mortality (A) and MACCE-free survival (B) stratified according to tertiles of the CSS, Mayo Clinic Risk Score (MCRS), Additive euroSCORE (EUROADD) and Logistic euroSCORE (EUROLOG). Kaplan-Meier curve showing the 5-year mortality (A) and MACCE-free survival (B) stratified according to tertiles of the CSS, Mayo Clinic Risk Score (MCRS), Additive euroSCORE (EUROADD) and Logistic euroSCORE (EUROLOG). No significant difference was observed between outcomes in Tertiles 1 and 2 (probability values not shown). *P (log-rank) values. Scot Garg et al. Circ Cardiovasc Interv. 2010;3: Copyright © American Heart Association, Inc. All rights reserved.

5 ROC curve for mortality (A) and MACCE (B) at 5-year follow-up for different risk scores. *P<0.001, †P<0.05, ¶P<0.01. ROC curve for mortality (A) and MACCE (B) at 5-year follow-up for different risk scores. *P<0.001, †P<0.05, ¶P<0.01. Scot Garg et al. Circ Cardiovasc Interv. 2010;3: Copyright © American Heart Association, Inc. All rights reserved.


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