1. Chapter 12: The Cell Cycle
AP Biology
Mrs. Ramon

2. The Life of a Cell

3. Chromosome Duplication

6. Cytokinesis in animal and plant cells

7. Prokaryotic Cell Division

9. Control of Cell Division
Physical factors that stimulate or inhibit cell division
Growth factors
Density-dependent inhibition

10. Control of Cell Division
Checkpoints
G1 (restriction pt.)
Ready to begin?
Failure to pass this checkpoint causes the cell to enter G0 G2
Ready to divide? M
Is cell division complete?

12. Cell Cycle Control

13. Cancer Cancer cells divide excessively and invade other tissues
“Immortal”
Example: HeLa Cells (1951)
Mutations in specific genes cause cells to become cancerous
Oncogenes
Gas pedal for cell growth
Mutation  gas pedal is stuck down
Tumor suppressors
Brakes for cell division
Mutation  brakes don’t work