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به نام خدا.

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Presentation on theme: "به نام خدا."— Presentation transcript:

1 به نام خدا

2 Impetigo Mupirocin; (bacitracin and neomycin, are less effective.)
numerous lesions or not responding to topical agents: oral antimicrobials effective against both S. aureus and S. pyogenes.

3 Impetigo

4 Folliculitis Local measures such as saline compresses and topical antibacterials (e.g., mupirocin)

5 Furuncles and Carbuncles
Most furuncles: moist heat. carbuncle, a furuncle with surrounding cellulitis or fever, or a furuncle located about the midface: an antistaphylococcal antibiotic (e.g., dicloxacillin). In a penicillin-allergic adult: clindamycin, or co-trimoxazole. Patients with moderate to severe disease are best treated with initial parenteral therapy (e.g., vancomycin, linezolid, or daptomycin)

6 Erysipelas Mild early: oral penicillin V (500 mg every 6 hours) or initial IM procaine penicillin (600,000 units once or twice daily). Erythromycin (250 to 500 mg orally every 6 hours) or other macrolides are suitable alternatives. More extensive: hospitalization and parenteral aqueous penicillin G (2,000,000 units every 6 hours). If differentiation from cellulitis is difficult: a PRP (nafcillin or oxacillin), a cephalo 1, or therapy against MRSA.

7 cellulitis Outpatient: PRP (nafcillin or oxacillin), cephalo 1
MRSA is suspected: clindamycin, TMP-SMX, doxycycline or minocycline + B-lactam (eg, amoxicillin), linezolid. Inpatient: PRP, cephalo 1 MRSA is suspected: vancomycin, linezolid, daptomycin, clindamycin

8 Diabetic Ulcers Mild: PO cephalexin, dicloxacillin, clindamycin
Moderate to severe: IV clindamycin plus a cephalo 3, clindamycin plus a fluoroquinolone, piperacillin-tazobactam, carbapenem, ampicillin-sulbactam, ticarcillin-clavulanate.

9 Cutaneous Abscess

10 Diabetic Ulcers

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12 Gastroenteritis ciprofloxacin, ofloxacin, levofloxacin, norfloxacin
Azithromycin

13 Typhoid Fever

14 Gastroenteritis (nosocomial)

15 CNS Infections (Meningitis)

16 CNS Infections (Brain Abscess)

17 CNS Infections (Shunt Infection)
vancomycin plus either cefepime, ceftazidime, or meropenem

18 CNS Infections (Subdural Empyema, Epidural Abscess)
vancomycin plus cefepime or ceftazidime + metronidazole or meropenem In spinal cases, anaerobic coverage is not required.

19 CNS Infections (Suppurative Intracranial Thrombophlebitis)
vancomycin plus cephalo 3 or 4 + metronidazole or meropenem

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