1. Cell Cycle Regulation & Cancer

2. Normal Cell Cycle ______________: proteins
_____ (Cyclin dependent kinases): enzymes
Cyclins and CDKs bind together to activate parts of the _________

3. Normal Cell Cycle __ checkpoint If something is wrong, cycle
will _______

4. ABNormal Cell Cycle ____________: when cell cycle regulations fail
Crowd out __________ cells
Spend less time in _____________

5. ABNormal Cell Cycle __________:cell death( if damaged)
Cancer: no apoptosis

6. Tumor: MASS OF CANCER CELLS
TWO TYPES OF TUMORS
_______: stays contained
__________: spread to nearby tissue or other organs

7. Why are Tumors bad? _____________: when tumors get a blood supply
_______ and_________go to tumor

8. Why are Tumors bad?
__________: pieces of tumor travel through blood to other organs

10. Causes of cancer
Gene _____________: changes in genes that control cell cycle
What causes these mutations?

11. Cancer causes ______________: cancer causing substances
EX: ________, ____________
_____________
EX: ____________, ____________

12. Cancer causes _________ EX: Human Papilloma Virus (_____) __________
EX: breast
___________ (no reason)

13. Treatments _________________
Diet, exercise, healthy weight, no smoking, limit alcohol
______________
Catch it early!
Mammograms
Pap smear
Colonoscopy

14. Treatments __________ Remove tumor and surrounding tissue ____________
Directly kill tumor
___________
Drug treatment

15. Incidence Rates:
Male
(From CDC)
Female

16. Death Rates:
Male
Female