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Obstetric and paediatric HIV surveillance data from the UK and Ireland

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Presentation on theme: "Obstetric and paediatric HIV surveillance data from the UK and Ireland"— Presentation transcript:

1 Obstetric and paediatric HIV surveillance data from the UK and Ireland

2

3 HIV prevalence among pregnant women England and Scotland only, 1997-2012 (PHE, HPS and ICH data)

4 21,226 pregnancies, diagnosed women since 1990, and reported
21,226 pregnancies, diagnosed women since 1990, and reported* by April 2016

5 Antenatal screening for HIV and impact

6 Timing of maternal HIV diagnosis UK & Ireland 1998-2015

7 Timing of maternal HIV diagnosis UK 1998-2015

8 Timing of diagnosis & ART at conception UK & Ireland 1998-2015

9 Sequential pregnancies by conception year, Pregnancies reported by end April 2016, UK and Ireland

10 Changing mode of delivery among all diagnosed women Deliveries reported by end April 2016*, UK births only

11 Uptake of antiretroviral therapy and MTCT rate by year of birth for 3703 infants born to diagnosed women

12 MTCT rates in diagnosed women, UK & Ireland 2000-2011

13 MTCT rates in diagnosed women, UK & Ireland 2000-2011

14 Infection status of children

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16 Infection status of children born to women diagnosed with HIV before delivery: UK & Ireland Births reported to NSHPC by April 2016

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18 Infection status of children born since 2000 to women diagnosed with HIV before delivery: UK Births reported to NSHPC by April 2016

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20 Infection status of children born since 2000 to women diagnosed with HIV before delivery: Ireland Births reported to NSHPC by April 2016

21 ART & premature delivery Diagnosed HIV positive women in UK & Ireland, 1990-2005

22 ART & congenital abnormalities: 1990-2007 data

23 NSHPC data on congenital abnormalities provided to Antiretroviral Pregnancy Registry (APR)

24 HIV infection and exposure in children in the UK and Ireland

25 NSHPC paediatric follow-up protocol

26 Collaborative HIV Paediatric Study Started in 2000, a collaboration between NSHPC, MRC Clinical Trials Unit and centres looking after infected children

27

28 Follow up of uninfected children exposed to ART: CHART study 2002-05

29 First audit of perinatal HIV transmissions 2002-05

30 Perinatal HIV audit – UK births since 2006

31 The role of NSHPC: public health surveillance & epidemiological and clinical research / audit

32 Ethics MREC/04/2/009

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