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Impact of Post-Transplant Response and Minimal Residual Disease on Survival in Myeloma with High-Risk Cytogenetics  Rajshekhar Chakraborty, Eli Muchtar,

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Presentation on theme: "Impact of Post-Transplant Response and Minimal Residual Disease on Survival in Myeloma with High-Risk Cytogenetics  Rajshekhar Chakraborty, Eli Muchtar,"— Presentation transcript:

1 Impact of Post-Transplant Response and Minimal Residual Disease on Survival in Myeloma with High-Risk Cytogenetics  Rajshekhar Chakraborty, Eli Muchtar, Shaji K. Kumar, Dragan Jevremovic, Francis K. Buadi, David Dingli, Angela Dispenzieri, Suzanne R. Hayman, William J. Hogan, Prashant Kapoor, Martha Q. Lacy, Nelson Leung, Morie A. Gertz  Biology of Blood and Marrow Transplantation  Volume 23, Issue 4, Pages (April 2017) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Correlation between post-transplant response and MRD status.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Impact of sCR on PFS (A; top left) and OS (B; top right) and impact of MRD on PFS (C; bottom left) and OS (D; bottom right). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Impact of sCR on PFS (A; top left) and OS (B; top right) and impact of MRD on PFS (C; bottom left) and OS (D; bottom right) in the subgroup of patients with deletion(17p). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Impact of sCR on PFS (A; top left) and OS (B; top right) and impact of MRD on PFS (C; bottom left) and OS (D; bottom right) in the subgroup of patients with t(4;14). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

6 Figure 5 Impact of sCR on PFS (A; top left) and OS (B; top right) and impact of MRD on PFS (C; bottom left) and OS (D; bottom right) in the subgroup of patients with ≥2 HR abnormalities. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions


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