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Independent validation of the prognostic value of cancer stem cell marker expression and hypoxia-induced gene expression for patients with locally advanced.

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Presentation on theme: "Independent validation of the prognostic value of cancer stem cell marker expression and hypoxia-induced gene expression for patients with locally advanced."— Presentation transcript:

1 Independent validation of the prognostic value of cancer stem cell marker expression and hypoxia-induced gene expression for patients with locally advanced HNSCC after postoperative radiotherapy  Annett Linge, Steffen Löck, Constanze Krenn, Steffen Appold, Fabian Lohaus, Alexander Nowak, Volker Gudziol, Gustavo B. Baretton, Frank Buchholz, Michael Baumann, Mechthild Krause  Clinical and Translational Radiation Oncology  Volume 1, Pages (December 2016) DOI: /j.ctro Copyright © 2016 The Authors Terms and Conditions

2 Fig. 1 (A–C) Kaplan-Meier estimates of (A) loco-regional control (LRC), (B) freedom of distant metastases (DM) and (C) overall survival (OS) for the training and validation cohort. Clinical and Translational Radiation Oncology 2016 1, 19-26DOI: ( /j.ctro ) Copyright © 2016 The Authors Terms and Conditions

3 Fig. 2 (A–I) Kaplan-Maier estimates of loco-regional control (LRC) for the validation cohort stratified for (A) HPV16 DNA status, (B) chemotherapy, (C–F) cancer stem cell (CSC) marker expression, (G and H) hypoxia-related gene classification and (I) combined risk. Gene names are indicated using italics. Clinical and Translational Radiation Oncology 2016 1, 19-26DOI: ( /j.ctro ) Copyright © 2016 The Authors Terms and Conditions


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