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by Alexander Kulik, Ian G. Burwash, Varun Kapila, Thierry G

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1 Long-Term Outcomes After Valve Replacement for Low-Gradient Aortic Stenosis
by Alexander Kulik, Ian G. Burwash, Varun Kapila, Thierry G. Mesana, and Marc Ruel Circulation Volume 114(1 suppl):I-553-I-558 July 4, 2006 Copyright © American Heart Association, Inc. All rights reserved.

2 Figure 1. Survival (A) and the incidence of persistent or recurrent CHF (B) in patients with and without LGAS after AVR. *Hazard ratio adjusted for left ventricular function, age, atrial fibrillation, preoperative NYHA functional class, coronary artery disease, smoking, and insulin-dependent diabetes mellitus. Figure 1. Survival (A) and the incidence of persistent or recurrent CHF (B) in patients with and without LGAS after AVR. *Hazard ratio adjusted for left ventricular function, age, atrial fibrillation, preoperative NYHA functional class, coronary artery disease, smoking, and insulin-dependent diabetes mellitus. AVR indicates, aortic valve replacement; CHF, congestive heart failure; CI, confidence interval; LGAS, low-gradient aortic stenosis. Alexander Kulik et al. Circulation. 2006;114:I-553-I-558 Copyright © American Heart Association, Inc. All rights reserved.

3 Figure 2. Impact of PPM on survival (A) and the incidence of persistent or recurrent CHF (B) after AVR in patients with LGAS. *Hazard ratio adjusted for LV function, age, atrial fibrillation, preoperative heart failure functional class, coronary artery disease, smoking, and insulin-dependent diabetes mellitus. Figure 2. Impact of PPM on survival (A) and the incidence of persistent or recurrent CHF (B) after AVR in patients with LGAS. *Hazard ratio adjusted for LV function, age, atrial fibrillation, preoperative heart failure functional class, coronary artery disease, smoking, and insulin-dependent diabetes mellitus. IEOA indicate indexed effective orifice area; PPM, prosthesis–patient mismatch. Alexander Kulik et al. Circulation. 2006;114:I-553-I-558 Copyright © American Heart Association, Inc. All rights reserved.

4 Figure 3. Impact of PPM on LV mass regression after AVR among patients with and without LGAS. LV indicates left ventricle.*P=0.037 refers to the comparison of PPM vs no PPM in LGAS patients. †P=0.1 refers to the comparison of PPM vs no PPM in no LGAS patients. Figure 3. Impact of PPM on LV mass regression after AVR among patients with and without LGAS. LV indicates left ventricle.*P=0.037 refers to the comparison of PPM vs no PPM in LGAS patients. †P=0.1 refers to the comparison of PPM vs no PPM in no LGAS patients. Alexander Kulik et al. Circulation. 2006;114:I-553-I-558 Copyright © American Heart Association, Inc. All rights reserved.


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