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HIV/HCV Co-Infection Case

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Presentation on theme: "HIV/HCV Co-Infection Case"— Presentation transcript:

1 HIV/HCV Co-Infection Case

2 Disclosures

3

4

5

6 Treatment History

7 Laboratory Values

8 SVR in HIV/HCV Pts According to IL28B

9 Factors Associated with SVR in HIV HCV Treated Pts.

10 IL-28B and DAA

11 Laboratory Values

12 Any other issues that need to be addressed before treatment?

13 Insulin Resistance Influences Response to Treatment with PegIFN/RBV in HIV/HCV Co-Infected Patients

14 Insulin Resistance Influences Response to Re-Treatment with PegIFN/RBV in HIV/HCV Co-Infected Patients

15 Multi-variable Analysis Outcome = SVR

16 Does Vitamin D Play a Role?

17 Does Vitamin D Play a Role?

18

19 June 2011

20 What do you recommend to this HIV-HCV cirrhotic patient?

21 Is the patient’s HIV regimen compatible with DAA?

22 DAA and co-infected patients

23 Telaprevir and co-infected: Study 110

24 Telaprevir and co-infected: Study 110

25 Boceprevir and co-infected

26 Boceprevir and co-infected

27 Pharmacokinetic interactions

28 Summer 2011

29 HCV viral load

30 CBC

31 Cytopenias and DAA

32 What would you recommend?

33 Growth factors and hepatitis C treatment

34 Growth factors and hepatitis C treatment

35 EPO

36 G-CSF

37 Thrombopoietic agents

38 CBC

39 January 2012

40 RGT

41 Telaprevir response guided therapy (RGT)

42 February 13th 2012


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