1. Professor Chris Whitty CB FMedSci Chief Scientific Adviser
The future of the NIHR
NIHR: 10 years of delivering health
and care research for the nation
QEII Centre, London
Wednesday 18 May 2016
Professor Chris Whitty CB FMedSci
Chief Scientific Adviser
Department of Health

2. Building on 10 remarkable years
The extraordinary advances in health are based on evidence and science, properly applied.
Most health interventions depend on science from multiple disciplines from the most basic to the most applied.
Future advances need to take account of changing need, new threats, new scientific opportunities.

3. Age-standardised mortality rates England and Wales (ONS 2014)

4. Ten leading causes of death in females, 2003-2013, England & Wales (ONS)

5. Must take account of distribution of need
Must take account of distribution of need. Dementia in women (L), heart disease (R)

6. Population 85 and over: 1992, 2015, 2033 (ONS).

7. Spend by UK public funder
Basic research
Applied research
Basic research
Applied research
Data taken from NIHR Dashboard for Financial Year and does not include the PRP and several new NIHR funding initiatives (eg. HPRUs) that started in 2014.
The update of the UKCRC report for Calendar Year 2014 is currently in preparation and will be available in shortly. This will include the entire DH R&D spend.
MRC
NIHR
Research spend 2013/2014

8. NIHR-Supported Facilities
Newcastle
Leeds
Leicester
Peninsula
Bradford
Manchester
Sheffield
Liverpool
Nottingham
Birmingham
Oxford
Cambridge
London
Bristol
Brighton
Southampton
Exeter
NIHR Biomedical Research Units
NIHR Health Protection Research Units
NIHR Biomedical Research Centres
NIHR Blood and Transplant Research Units
NIHR Healthcare Technology Co- operatives
NIHR Diagnostic Evidence Co-operatives
NIHR-supported Clinical Research Facilities
NIHR School for Public Health Research
NIHR School for Primary Care Research
NIHR/CR-UK Experimental Cancer Medicine Centres
NIHR Surgical Reconstruction and Microbiology Research Centre
NIHR Collaborations for Leadership in Applied Health Research and Care
NIHR Biomedical Research Units
Newcastle – dementia
Leeds – musculoskeletal
Central Manchester – musculoskeletal
Liverpool – gastrointestinal
Nottingham – hearing/respiratory/gastrointestinal
Leicester – cardiovascular/respiratory/nutrition
Birmingham – gastrointestinal
Bristol – cardiovascular/nutrition
Oxford – musculoskeletal
Southampton – respiratory
London Imperial – cardiovascular/respiratory
Barts – cardiovascular
UCL – dementia
South London and Maudsley - dementia
NIHR Health Protection Research Units
University College London - Blood Borne and Sexually Transmitted Infections
University of Newcastle upon Tyne - Chemical and Radiation Threats and Hazards
King’s College London - Emergency Preparedness and Response
University of Liverpool - Emerging and Zoonotic Infections
London School of Hygiene and Tropical Medicine - Environmental Change and Health
University of Liverpool - Gastrointestinal Infections
King’s College London - Health Impact of Environmental Hazards
Imperial College London - Healthcare Associated Infections and Antimicrobial Resistance
University of Oxford - Healthcare Associated Infections and Antimicrobial Resistance
London School of Hygiene and Tropical Medicine - Immunisation
Imperial College London - Respiratory Infections
University of Bristol - Evaluation of Interventions
Imperial College London - Modelling Methodology
NIHR Biomedical Research Centres
Newcastle
Oxford
Cambridge
Southampton
Imperial
UCLH
Great Ormond St
Moorfields
Guy’s and St Thomas
Royal Marsden
South London and Maudsley
NIHR Blood and Transplant Research Units
University of Bristol – New Red Blood Cell Products
University of Cambridge – Donor Health and Genomics
University of Cambridge – Organ Donation and Transplantation
University College London – Stem Cells and Immunotherapies
NIHR Healthcare Technology Co-operatives
Birmingham
Bradford
Leeds
Nottingham
Sheffield
Barts
Guy’s & St Thomas’
NIHR/CR-UK Experimental Cancer
Medicine Centres
Leicester
Barts/ Brighton
ICR
King’s College London
UCL
Manchester
NIHR Diagnostic Evidence Co-operatives
NIHR-supported Clinical Research Facilities
Alder Hey
Brighton and Sussex
The Christie
Exeter
Maudsley
Oxford cognitive health
South Manchester respiratory
and allergy
NIHR School for Public Health Research
University of Sheffield – Lead Partner
University of Cambridge
University of Liverpool / Lancaster
NE consortium FUSE
London School of Hygiene and Tropical Medicine
University College London
University of Bristol
University of Exeter
NIHR School for Primary Care Research
University of Oxford – Lead Partner
University of Manchester
Keele University
University of Nottingham
University of Southampton
University of Newcastle-Upon-Tyne
NIHR Collaborations for Leadership in
Applied Health Research and Care
East of England
East Midlands
Greater Manchester
North Thames
North West Coast
North West London
South London
South West Peninsula
West
West Midlands
Wessex
Yorkshire and Humber
NIHR Surgical Reconstruction and Microbiology Research Centre

9. NIHR Clinical Research Network
15 Local Clinical Research Networks (LCRNs) .
Boundaries align with AHSNs.
Essential for the testing of new interventions for the NHS in areas of clinical need.
Also important for industry and charities.

10. The future of the future: training
Research training has to be appropriate for when trainees become independent scientists.
Need to adapt to current pressures on clinical and non-clinical scientists.
Need to address the falloff in women in science at postdoctoral level.

11. Many fields rapidly progressing driven by new and old sciences, supported by NIHR. This will continue over the next 10 years.
Stroke mortality