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Volume 139, Issue 1, Pages (January 2011)

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1 Volume 139, Issue 1, Pages 190-193 (January 2011)
Beneficial Effects of Treatment With Anti-IgE Antibodies (Omalizumab) in a Patient With Severe Asthma and Negative Skin-Prick Test Results  Dr Maarten van den Berge, MD, PhD, Dr Ronald G. Pauw, MD, Dr Jan G.R. de Monchy, MD, PhD, Dr Cees A. van Minnen, MD, Dr Dirkje S. Postma, MD, PhD, Dr Huib A.M. Kerstjens, MD, PhD  CHEST  Volume 139, Issue 1, Pages (January 2011) DOI: /chest Copyright © 2011 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Chest radiograph at time of first exacerbation.
CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

3 Figure 2 A bronchial biopsy specimen showing a thickened basement membrane and diffuse tissue eosinophilia (arrows) compatible with asthma. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

4 Figure 3 All FEV1 measurements carried out between 2000 and The FEV1 improved and remained stable after the start of omalizumab in December After withdrawal of omalizumab, FEV1 deteriorated. Finally, FEV1 improved again when omalizumab was restarted. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions


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