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Volume 142, Issue 1, Pages (July 2012)

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1 Volume 142, Issue 1, Pages 63-75 (July 2012)
Predictive Value of Interferon-γ Release Assays and Tuberculin Skin Testing for Progression From Latent TB Infection to Disease State  Roland Diel, MD, MPH, Robert Loddenkemper, MD, FCCP, Albert Nienhaus, MD, MPH  CHEST  Volume 142, Issue 1, Pages (July 2012) DOI: /chest Copyright © 2012 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Flow diagram for study selection. IGRA = interferon-γ release assay; NPV = negative predictive value; PPV = positive predictive value; TST = tuberculin skin test. CHEST  , 63-75DOI: ( /chest ) Copyright © 2012 The American College of Chest Physicians Terms and Conditions

3 Figure 2 PPV in % for progression to active TB of commercial IGRAs (all studies). df = degrees of freedom. See Figure 1 legend for expansion of other abbreviations. CHEST  , 63-75DOI: ( /chest ) Copyright © 2012 The American College of Chest Physicians Terms and Conditions

4 Figure 3 PPV in % for progression to active TB of commercial IGRAs (high-risk groups only). See Figure 1 and 2 legends for expansion of abbreviations. CHEST  , 63-75DOI: ( /chest ) Copyright © 2012 The American College of Chest Physicians Terms and Conditions

5 Figure 4 PPV in % for progression to active TB of TST (all studies). See Figure 1 and 2 legends for expansion of abbreviations. CHEST  , 63-75DOI: ( /chest ) Copyright © 2012 The American College of Chest Physicians Terms and Conditions

6 Figure 5 PPV in % for progression to active TB of TST (high-risk groups only). See Figure 1 and 2 legends for expansion of abbreviations. CHEST  , 63-75DOI: ( /chest ) Copyright © 2012 The American College of Chest Physicians Terms and Conditions

7 Figure 6 NPV in % for progression to active TB of commercial IGRAs. See Figure 1 and 2 legends for expansion of abbreviations. CHEST  , 63-75DOI: ( /chest ) Copyright © 2012 The American College of Chest Physicians Terms and Conditions

8 Figure 7 NPV in % for progression to active TB of TST. See Figure 1 and 2 legends for expansion of abbreviations. CHEST  , 63-75DOI: ( /chest ) Copyright © 2012 The American College of Chest Physicians Terms and Conditions


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