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IHC-breast cancer subtypes of invasive ductal carcinoma with predominant intraductal component as an insignificant prognostic factor: A register-based.

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Presentation on theme: "IHC-breast cancer subtypes of invasive ductal carcinoma with predominant intraductal component as an insignificant prognostic factor: A register-based."— Presentation transcript:

1 IHC-breast cancer subtypes of invasive ductal carcinoma with predominant intraductal component as an insignificant prognostic factor: A register-based study from Korea  Jung Sun Lee, Minkyung Oh, SeungSang Ko, Min Ho Park, Se Jeong Oh, Jeong-Yoon Song, SeokWon Kim  Cancer Treatment and Research Communications  Volume 7, Pages (January 2016) DOI: /j.ctrc Copyright © 2016 Elsevier Ltd Terms and Conditions

2 Fig. 1 Kaplan–Meier Survival curves according to DCIS subtypes In DCIS, HER2 expression (HR=1.09, 95%CI; 0.55–2.14) showed the worst overall survival compared with TNBC (HR=1), luminal A (HR=0.56, 95%CI; 0.31–1.02), or luminal B (HR=0.69, 95%CI; 0.32–1.48) (A). No significant differences in breast cancer specific survival among tumor characteristics were observed in DCIS (p=0.13) (B). Cancer Treatment and Research Communications 2016 7, 52-57DOI: ( /j.ctrc ) Copyright © 2016 Elsevier Ltd Terms and Conditions

3 Fig. 2 Kaplan–Meier Survival curves according to IDC subtypes TNBC (HR=1.0) showed the worst overall survival compared with luminal A (HR=0.44, 95%CI; 0.34–0.54), luminal B (HR=0.63, 95%CI; 0.46–0.84) or HER2 expressing breast cancer (HR=0.70, 95%CI; 0.52–0.95) in IDC (A), and differences in breast cancer specific survival were observed in IDC (p<0.001)(B). Cancer Treatment and Research Communications 2016 7, 52-57DOI: ( /j.ctrc ) Copyright © 2016 Elsevier Ltd Terms and Conditions

4 Fig. 3 Kaplan–Meier Survival curves according to DCIS-IDC subtypes DCIS-IDC, no differences in overall survival were observed among breast cancer subtypes (p=0.31) (A). No significant differences in breast cancer specific survival among tumor characteristics were observed DCIS-IDC (p=0.80) (B). Cancer Treatment and Research Communications 2016 7, 52-57DOI: ( /j.ctrc ) Copyright © 2016 Elsevier Ltd Terms and Conditions


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